“Interferon magic” in ocular surface squamous neoplasia
نویسندگان
چکیده
منابع مشابه
Ocular Surface Squamous Neoplasia
The ocular surface is composed of the conjunctiva and the cornea. The conjunctiva is a mucous membrane which covers the globe and inner part of the eyelids. The morphology of conjunctival epithelial cells are nonkeratinized stratified epithelia which vary from cuboidal over the tarsus, to columnar in the fornices, to squamous epithelia on the globe. Goblet cells account for up to 10% of the bas...
متن کاملOcular surface squamous neoplasia treated with topical interferon α 2b.
To cite: Pujari A. BMJ Case Rep Published online: [please include Day Month Year] doi:10.1136/bcr-2016218344 DESCRIPTION A 64-year-old male patient presented with fleshy lesion over the right temporal conjunctiva for the past 3 months with a gradual increase in size. History of trauma and pain was absent, and past history did not reveal any significant ocular/systemic morbidities. Right eye exa...
متن کاملTopical Interferon Alpha-2b for Treatment of Noninvasive Ocular Surface Squamous Neoplasia with 360° Limbal Involvement
PURPOSE To report the results of topical interferon alpha-2b (IFNα2b) for the treatment of ocular surface squamous neoplasia (OSSN) with 360° limbal involvement. METHODS In a prospective observational study, five patients with biopsy proven primary or recurrent OSSN with 360° limbal involvement received topical IFNα2b (3 million IU/ml, 4 times daily) and were followed from 8 to 12 months. Out...
متن کاملEpidemiology of ocular surface squamous neoplasia in Africa
OBJECTIVES To describe the epidemiology and an aetiological model of ocular surface squamous neoplasia (OSSN) in Africa. METHODS Systematic and non-systematic review methods were used. Incidence was obtained from the International Agency for Research on Cancer. We searched PubMed, EMBASE, Web of Science and the reference lists of articles retrieved. Meta-analyses were conducted using a fixed-...
متن کاملElevated expression of ABCB5 in ocular surface squamous neoplasia.
ATP-binding cassette subfamily B member 5 (ABCB5) is a new member of the ATP-binding cassette superfamily and has been reported as a novel marker for limbal stem cell (LSC), which is essential for corneal homeostasis. ABCB5 expression has also been discovered in the subpopulation of several cancer cells containing the cancer stem cell (CSC). However, the pathogenetic relationship between LSC an...
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ژورنال
عنوان ژورنال: Kerala Journal of Ophthalmology
سال: 2018
ISSN: 0976-6677
DOI: 10.4103/kjo.kjo_81_18